Domain architecture for Protein

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Full-length Protein Ortholog Groups for

D1C9N4

Gene name: Sthe_3127 / D1C9N4_SPHTD

Species: Sphaerobacter thermophilus (strain DSM 20745 / S 6022), 479434

This protein is part of 81 full-length protein ortholog groups

View protein in UniProt




Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
263 Acholeplasma oculi A0A061AGV2 Aocu_01040 132 1.0 1.0 Response Regulators Consisting Of A Chey-Like Receiver Domain And A Winged-Helix Dna-Binding Domain
263 Sphaerobacter thermophilus D1C1S1 Sthe_0751 132 1.0 0.883 Two Component Transcriptional Regulator, Winged Helix Family
263 Sphaerobacter thermophilus D1C280 Sthe_0910 132 0.159 - Two Component Transcriptional Regulator, Winged Helix Family
263 Sphaerobacter thermophilus D1C747 Sthe_0369 132 0.142 - Two Component Transcriptional Regulator, Winged Helix Family
263 Sphaerobacter thermophilus D1C556 Sthe_1941 132 0.129 - Two Component Transcriptional Regulator, Winged Helix Family
263 Sphaerobacter thermophilus D1C6J6 Sthe_2197 132 0.117 - Two Component Transcriptional Regulator, Winged Helix Family
263 Sphaerobacter thermophilus D1C9N4 Sthe_3127 132 0.065 - Two Component Transcriptional Regulator, Winged Helix Family
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
558 Brachypodium distachyon A0A0Q3GW57 100834563 61 1.0 1.0 Response Regulatory Domain-Containing Protein
558 Brachypodium distachyon I1IBT9 100845507 61 1.0 1.0 Response Regulatory Domain-Containing Protein
558 Brachypodium distachyon I1IZT4 100825781 61 1.0 1.0 Response Regulatory Domain-Containing Protein
558 Brachypodium distachyon I1HVA2 100839190 61 1.0 1.0 Response Regulatory Domain-Containing Protein
558 Brachypodium distachyon I1IFQ6 100843889 61 1.0 1.0 Response Regulatory Domain-Containing Protein
558 Brachypodium distachyon I1IUJ3 100830988 61 0.493 - Response Regulatory Domain-Containing Protein
558 Brachypodium distachyon A0A2K2CGU8 BRADI_5g12697v3 61 0.255 - Response Regulatory Domain-Containing Protein (Fragment)
558 Brachypodium distachyon I1HJL2 104583164 61 0.076 - Response Regulatory Domain-Containing Protein
558 Sphaerobacter thermophilus D1C6S1 Sthe_0243 61 1.0 1.0 Two Component Transcriptional Regulator, Luxr Family
558 Sphaerobacter thermophilus D1C683 Sthe_0182 61 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1CA30 Sthe_3273 61 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C7Y5 Sthe_2441 61 1.0 1.0 Response Regulator Receiver Protein
558 Sphaerobacter thermophilus D1C8D7 Sthe_2666 61 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C556 Sthe_1941 61 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C1C8 Sthe_0608 61 0.41 - Two Component Transcriptional Regulator, Luxr Family
558 Sphaerobacter thermophilus D1C482 Sthe_1615 61 0.365 - Two Component Transcriptional Regulator, Luxr Family
558 Sphaerobacter thermophilus D1C747 Sthe_0369 61 0.324 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C3I4 Sthe_1366 61 0.31 - Two Component Transcriptional Regulator, Luxr Family
558 Sphaerobacter thermophilus D1C280 Sthe_0910 61 0.29 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C1S1 Sthe_0751 61 0.278 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C6J6 Sthe_2197 61 0.271 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 61 0.266 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C9R5 Sthe_3158 61 0.233 - Two Component Transcriptional Regulator, Luxr Family
558 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 61 0.195 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C9N4 Sthe_3127 61 0.19 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1CA41 Sthe_3284 61 0.178 - Two Component Transcriptional Regulator, Winged Helix Family
558 Sphaerobacter thermophilus D1C6P9 Sthe_2252 61 0.084 - Response Regulator Receiver Protein
558 Sphaerobacter thermophilus D1C4X8 Sthe_1862 61 0.079 - Response Regulator Receiver Protein
558 Sphaerobacter thermophilus D1C5F4 Sthe_0031 61 0.05 - Response Regulator Receiver Protein
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
559 Oryza sativa Q8GVV6 RR8 59 1.0 1.0 Two-Component Response Regulator Orr8
559 Oryza sativa Q2HWH1 RR5 59 1.0 1.0 Two-Component Response Regulator Orr5
559 Oryza sativa Q6K9T0 RR3 59 1.0 1.0 Two-Component Response Regulator Orr3
559 Oryza sativa Q942A1 RR4 59 1.0 1.0 Two-Component Response Regulator Orr4
559 Oryza sativa Q6H468 RR11 59 1.0 1.0 Two-Component Response Regulator Orr11
559 Oryza sativa Q7XQA6 RR6 59 1.0 1.0 Two-Component Response Regulator Orr6
559 Oryza sativa Q2HWG1 RR12 59 0.94 - Two-Component Response Regulator Orr12
559 Oryza sativa Q2HWG0 RR13 59 0.92 - Two-Component Response Regulator Orr13
559 Oryza sativa Q0PVB3 RR7 59 0.71 - Two-Component Response Regulator Orr7
559 Oryza sativa Q2QXY3 RR10 59 0.474 - Two-Component Response Regulator Orr10
559 Oryza sativa Q2RAP3 RR9 59 0.469 - Two-Component Response Regulator Orr9
559 Oryza sativa Q2HWG4 RR1 59 0.374 - Two-Component Response Regulator Orr1
559 Oryza sativa Q6YVX7 RR2 59 0.321 - Two-Component Response Regulator Orr2
559 Sphaerobacter thermophilus D1C6P9 Sthe_2252 59 1.0 1.0 Response Regulator Receiver Protein
559 Sphaerobacter thermophilus D1C6S1 Sthe_0243 59 1.0 1.0 Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C388 Sthe_1270 59 1.0 1.0 Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C683 Sthe_0182 59 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C7Y5 Sthe_2441 59 1.0 1.0 Response Regulator Receiver Protein
559 Sphaerobacter thermophilus D1C556 Sthe_1941 59 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C1C8 Sthe_0608 59 0.404 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C482 Sthe_1615 59 0.358 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C8D7 Sthe_2666 59 0.356 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C9Z8 Sthe_3241 59 0.342 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C747 Sthe_0369 59 0.33 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C420 Sthe_1552 59 0.329 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C6A1 Sthe_0200 59 0.316 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C3I4 Sthe_1366 59 0.302 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C280 Sthe_0910 59 0.297 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C1S1 Sthe_0751 59 0.285 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C6J6 Sthe_2197 59 0.278 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 59 0.273 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C9R5 Sthe_3158 59 0.225 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C237 Sthe_0867 59 0.217 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C9N4 Sthe_3127 59 0.183 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1CA30 Sthe_3273 59 0.181 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1CA41 Sthe_3284 59 0.173 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 59 0.173 - Two Component Transcriptional Regulator, Winged Helix Family
559 Sphaerobacter thermophilus D1C9X5 Sthe_3218 59 0.13 - Two Component Transcriptional Regulator, Luxr Family
559 Sphaerobacter thermophilus D1C1G8 Sthe_0648 59 0.126 - Response Regulator Receiver Protein
559 Sphaerobacter thermophilus D1C8E6 Sthe_2675 59 0.106 - Response Regulator Receiver Protein
559 Sphaerobacter thermophilus D1C4X8 Sthe_1862 59 0.097 - Response Regulator Receiver Protein
559 Sphaerobacter thermophilus D1C9F7 Sthe_3049 59 0.087 - Response Regulator Receiver Protein
559 Sphaerobacter thermophilus D1C470 Sthe_1603 59 0.063 - Response Regulator Receiver And Antar Domain Protein
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
574 Actinidia chinensis A0A2R6QGT2 CEY00_Acc18177 52 1.0 1.0 Two-Component Response Regulator Like
574 Actinidia chinensis A0A2R6PDY3 CEY00_Acc29817 52 1.0 1.0 Two-Component Response Regulator Like
574 Actinidia chinensis A0A2R6RF63 CEY00_Acc06265 52 0.467 - Two-Component Response Regulator Like
574 Sphaerobacter thermophilus D1C556 Sthe_1941 52 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 52 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C8D7 Sthe_2666 52 0.356 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C1S1 Sthe_0751 52 0.342 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C747 Sthe_0369 52 0.33 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C280 Sthe_0910 52 0.302 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C6J6 Sthe_2197 52 0.288 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C683 Sthe_0182 52 0.271 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1C9N4 Sthe_3127 52 0.183 - Two Component Transcriptional Regulator, Winged Helix Family
574 Sphaerobacter thermophilus D1CA41 Sthe_3284 52 0.173 - Two Component Transcriptional Regulator, Winged Helix Family
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
516 Selaginella moellendorffii D8RSK6 PRR3 87 1.0 1.0 Pseudo Response Regulator
516 Sphaerobacter thermophilus D1CA30 Sthe_3273 87 1.0 0.761 Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C747 Sthe_0369 87 0.145 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C556 Sthe_1941 87 0.11 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C1S1 Sthe_0751 87 0.107 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 87 0.102 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C9N4 Sthe_3127 87 0.097 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C8D7 Sthe_2666 87 0.094 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1CA41 Sthe_3284 87 0.083 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 87 0.072 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C6J6 Sthe_2197 87 0.062 - Two Component Transcriptional Regulator, Winged Helix Family
516 Sphaerobacter thermophilus D1C683 Sthe_0182 87 0.056 - Two Component Transcriptional Regulator, Winged Helix Family
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
307 Melampsora larici-populina F4R5X1 MELLADRAFT_32907 81 1.0 1.0 Response Regulatory Domain-Containing Protein (Fragment)
307 Sphaerobacter thermophilus D1C8D7 Sthe_2666 81 1.0 0.663 Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C556 Sthe_1941 81 0.321 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C683 Sthe_0182 81 0.255 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C6J6 Sthe_2197 81 0.22 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C280 Sthe_0910 81 0.215 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C747 Sthe_0369 81 0.215 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 81 0.183 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C1S1 Sthe_0751 81 0.164 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1CA30 Sthe_3273 81 0.109 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1CA41 Sthe_3284 81 0.095 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C9N4 Sthe_3127 81 0.085 - Two Component Transcriptional Regulator, Winged Helix Family
307 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 81 0.058 - Two Component Transcriptional Regulator, Winged Helix Family
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
393 Sphaerobacter thermophilus D1CA30 Sthe_3273 53 1.0 0.554 Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C747 Sthe_0369 53 0.216 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C556 Sthe_1941 53 0.184 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C1S1 Sthe_0751 53 0.182 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 53 0.177 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C9N4 Sthe_3127 53 0.172 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C8D7 Sthe_2666 53 0.17 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1CA41 Sthe_3284 53 0.16 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 53 0.15 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C6J6 Sthe_2197 53 0.14 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C683 Sthe_0182 53 0.135 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C280 Sthe_0910 53 0.123 - Two Component Transcriptional Regulator, Winged Helix Family
393 Sphaerobacter thermophilus D1C6P9 Sthe_2252 53 0.064 - Response Regulator Receiver Protein
393 Tieghemostelium lacteum A0A151Z9U7 DLAC_09365 53 1.0 1.0 Response Regulator Receiver Domain-Containing Protein
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
416 Methanothermobacter thermautotrophicus O26987 MTH_901 52 1.0 1.0 Sensory Transduction Regulatory Protein
416 Sphaerobacter thermophilus D1C1S1 Sthe_0751 52 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 52 0.375 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C280 Sthe_0910 52 0.332 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C747 Sthe_0369 52 0.319 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C556 Sthe_1941 52 0.308 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C6J6 Sthe_2197 52 0.298 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C9N4 Sthe_3127 52 0.257 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 52 0.237 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1CA41 Sthe_3284 52 0.219 - Two Component Transcriptional Regulator, Winged Helix Family
416 Sphaerobacter thermophilus D1CA30 Sthe_3273 52 0.193 - Two Component Transcriptional Regulator, Winged Helix Family
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
621 Sorghum bicolor A0A1Z5RBR0 SORBI_3006G021400 45 1.0 1.0 Response Regulatory Domain-Containing Protein
621 Sorghum bicolor A0A1B6PJM5 SORBI_3006G021500 45 0.82 - Response Regulatory Domain-Containing Protein
621 Sorghum bicolor A0A1Z5RBV0 SORBI_3006G021300 45 0.82 - Response Regulatory Domain-Containing Protein
621 Sphaerobacter thermophilus D1CA30 Sthe_3273 45 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
621 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 45 0.193 - Two Component Transcriptional Regulator, Winged Helix Family
621 Sphaerobacter thermophilus D1C9N4 Sthe_3127 45 0.188 - Two Component Transcriptional Regulator, Winged Helix Family
621 Sphaerobacter thermophilus D1CA41 Sthe_3284 45 0.176 - Two Component Transcriptional Regulator, Winged Helix Family
621 Sphaerobacter thermophilus D1C6P9 Sthe_2252 45 0.082 - Response Regulator Receiver Protein
Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description
493 Sphaerobacter thermophilus D1C683 Sthe_0182 45 1.0 1.0 Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C8D7 Sthe_2666 45 0.314 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C747 Sthe_0369 45 0.29 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C556 Sthe_1941 45 0.287 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C280 Sthe_0910 45 0.283 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C6J6 Sthe_2197 45 0.266 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C5Q5 Sthe_2027 45 0.257 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C1S1 Sthe_0751 45 0.242 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C9N4 Sthe_3127 45 0.192 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1C3Q5 Sthe_1437 45 0.192 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1CA41 Sthe_3284 45 0.157 - Two Component Transcriptional Regulator, Winged Helix Family
493 Sphaerobacter thermophilus D1CA30 Sthe_3273 45 0.15 - Two Component Transcriptional Regulator, Winged Helix Family
493 Spizellomyces punctatus A0A0L0HTN2 SPPG_01656 45 1.0 1.0 Response Regulatory Domain-Containing Protein
493 Spizellomyces punctatus A0A0L0H4X3 SPPG_08409 45 0.395 - Response Regulatory Domain-Containing Protein
493 Spizellomyces punctatus A0A0L0HCQ7 SPPG_06366 45 0.284 - Response Regulatory Domain-Containing Protein
493 Spizellomyces punctatus A0A0L0HLT3 SPPG_02860 45 0.128 - Response Regulatory Domain-Containing Protein